MersV1, Main, Exploration, bibRecord, 000715

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea

Identifieur interne : 000715 ( Main/Exploration ); précédent : 000714; suivant : 000716

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea

Auteurs : Jun Yong Choi [Corée du Sud] ; Jin Ok Oh [Corée du Sud] ; Jin Young Ahn [Corée du Sud] ; Heun Choi [Corée du Sud] ; Jung Ho Kim [Corée du Sud] ; Hye Seong [Corée du Sud] ; Su Jin Jeong [Corée du Sud] ; Nam Su Ku [Corée du Sud] ; Joon-Sup Yeom [Corée du Sud] ; Jae-Phil Choi [Corée du Sud]

Source :

Clinical and Experimental Vaccine Research [ 2287-3651 ] ; 2019.

RBID : PMC:6369131

Abstract

We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369131

DOI: 10.7774/cevr.2019.8.1.86
PubMed: 30775355
PubMed Central: 6369131

Affiliations:

Corée du Sud

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.</p>
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Serveur d'exploration MERS

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea

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Abstract

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	Serveur d'exploration MERS
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